All Publications & News
Clara Basto, prix Peters at the « Journées JJCC de la Fonation ARC »
Clara Basto, PhD student of the team of Gerard Mazón/Eric Le Cam under the supervision of Pauline Dupaigne has been
Christophe Massard and Sergey Nikolaev | Internal Seminars at Gustave Roussy
Christophe Massard DITEP – Drug Drug development department “Phase I in 2025” & Sergey Nikolaev New UMR – Cancer Data
ANR AAPG 2026 closing on 14 October 2026
AAPG 2026 of the ANR (1st phase) closing on 14th October
Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis
The AOUFOUCHI team participate in this article : Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of
Effect of Mismatch repair deficiency on metastasis occurrence in a syngeneic mouse model
This work, led by P. Laplante in Kannouche's team, shows how mismatch repair deficiency causes high mutation rates and microsatellite
Re-investigating PLK1 inhibitors as antimitotic agents
Polo-like kinase 1 (PLK1) plays key roles during mitosis, prompting the development of PLK1 inhibitors for anticancer therapy. We recently
Senataxin and DNA-PKcs redundantly promote non-homologous end joining repair of DNA double strand breaks during V(D)J recombination
G. Matos Rodrigues co-authors this work of the Sleckman lab on the roles of Senataxin and DNA-PKcs during DSB by
Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
The Gavet team developed a FRET-based sensor to specifically monitor Chk1 activity during replication stress (RS). Basal Chk1 activity during
L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC
L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025
Next Unit Lab Meeting
Prochaine réunion d'unité 13/10/2025 Salle Roger Monier 13h30 Speaker: Nataliya PETRYK “ Revealing the mechanisms linking genome replication and epigenome
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
N. Petryk co-authors this review of the mechanisms of DNA methylation in mammals and its biological importance.
Unit Seminar: Masato Kanemaki
Masato Kanemaki from the University of Tokyo. (NEW TIME!) Friday, 17 October at 10:30 at Salle Roger Monier
Next Thesis Defences
December 15th 2025: Clara Basto Molecular study on the roles of RAD51 and its partner proteins in the management of
Changes in the architecture and abundance of replication intermediates at UV-stalled replication forks in human cells
This is a collaborative effort of the Kannouche and Mazon/LeCam teams of the unit. DNA lesions during S phase challenge