
TASP1-mediated cleavage of REV3L enhances the activity of DNA polymerase ζ in mammalian cells
The Kannouche team contributed to this study, published in Cancer Cell (2026), reporting the results of the ICARUS-LUNG01 Phase II trial: Efficacy, Safety, and Biomarker Analysis of Datopotamab Deruxtecan in Advanced Non-Small Cell Lung Cancer. The study evaluates the clinical activity, safety profile, and predictive biomarkers associated with datopotamab deruxtecan in patients with advanced non-small cell lung cancer.





