All Publications & News

Human RAD52 stimulates the RAD51-mediated homology search

In a work led by A. Muhammad, a PhD student under P. Dupaigne supervision in the team, we show that

Emmanuelle Pessagué | SEMINAIRE SIRIC EPICURE

Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation 17 Octobre 2025 à 11h30 - Salle Roger

Gustave Roussy Cancer Research Lectures | Reuben Harris

"DNA adducting carcinogens exacerbate APOBEC mutagenesis and carcinogenesis" Reuben Harris (UT San Antonio, US) 01/10/2025 at 11h Salle Pierre Denoix

Unit Seminar: Masato Kanemaki

Masato Kanemaki from the University of Tokyo. (NEW TIME!) Friday, 17 October at 10:30 at Salle Roger Monier

Contribution of p53-dependent and -independent mechanisms to upregulation of p21 in Fanconi anemia

F. Rosselli's team shows in this article how abnormal p21 expression in Fanconi anemia (FA) contributes to bone marrow failure

Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients

This article is a collaboration of the Kannouche team with the Gustave Roussy's team of S. Nikolaev. Xeroderma pigmentosum (XP)

EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation

B. Rondinelli co-authors this article of the D'Andrea lab describing the roles of EZH2 at stalled replication forks.

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

G. Matos Rodrigues co-authors this work led by the Schatz lab describing the roles of ELOF1 during somatic hypermutation and

Effect of Mismatch repair deficiency on metastasis occurrence in a syngeneic mouse model

This work, led by P. Laplante in Kannouche's team, shows how mismatch repair deficiency causes high mutation rates and microsatellite

Senataxin and DNA-PKcs redundantly promote non-homologous end joining repair of DNA double strand breaks during V(D)J recombination

G. Matos Rodrigues co-authors this work of the Sleckman lab on the roles of Senataxin and DNA-PKcs during DSB by

SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells

In this article, the Mazon's team PhD student H. Dorison goes deeper in the understanding of the SUMO-mediated regulation of

Abasic site-peptide cross-links are blocking lesions repaired by AP endonucleases

A. Ishchenko participates in this study of the fate of the DNA-protein crosslinks generated by the activity of AP endonucleases

Changes in the architecture and abundance of replication intermediates at UV-stalled replication forks in human cells

This is a collaborative effort of the Kannouche and Mazon/LeCam teams of the unit. DNA lesions during S phase challenge

ANR AAPG 2026 closing on 14 October 2026

AAPG 2026 of the ANR (1st phase) closing on 14th October