Seminar | Matinée de l’Intégrité du Génome
Seminar « Functional Genomics of Microsatellite Unstable Tumors and Therapeutic Target Discovery » by Gabriele Picco (Sanger Institute) 11:00 05/12/2025 at Roger Monier.
Seminar « Functional Genomics of Microsatellite Unstable Tumors and Therapeutic Target Discovery » by Gabriele Picco (Sanger Institute) 11:00 05/12/2025 at Roger Monier.
Clara Basto, PhD student of the team of Gerard Mazón/Eric Le Cam under the supervision of Pauline Dupaigne has been awarded the « Prix coup de coeur du Jury » for her talk during the 29th « Journées Jeunes Chercheurs de la Fondation ARC ».
Masato Kanemaki from the University of Tokyo. (NEW TIME!)
Friday, 17 October at 10:30 at Salle Roger Monier
December 15th 2025: Clara Basto
Molecular study on the roles of RAD51 and its partner proteins in the management of arrested replication forks
(Mazon/Dupaigne Team)
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December 17th 2025: Basile Guignier
Role of REV3L, the catalytic subunit of DNA polymerase Zeta, in the stability of difficult-to-replicate sequences in mammals
(Kannouche Team)
Prochaine réunion d’unité
13/10/2025
Salle Roger Monier 13h30
Speaker: Nataliya PETRYK
“ Revealing the mechanisms linking genome replication and epigenome maintenance «
AAPG 2026 of the ANR (1st phase) closing on 14th October
The S. Gad group of Ishchenko team leads this work on a novel genetic condition linked to Hereditary renal cell carcinomas (RCC). The team identified a frameshift mutation in NBR1, a gene involved in autophagy. Their findings suggest NBR1 as a potential new RCC predisposition gene, pending further validation.
OK-seq is a technique that sequences strand-specific Okazaki fragments to map replication initiation and termination in mammalian genomes. It quantifies fork directionality, revealing replication dynamics at high resolution. N. Petryk team contributes to this work to provide detailed protocols for OK-seq in human cells and yeast, alongside bioinformatics pipelines.
« DNA adducting carcinogens exacerbate APOBEC mutagenesis and carcinogenesis »
Reuben Harris (UT San Antonio, US)
01/10/2025 at 11h
Salle Pierre Denoix (15th Floor Gustave Roussy main builiding)
The 7th German-French DNA repair meeting will be held this November 5th-7th in Paris. The unit is this time involved as hosting/organizing committee of the meeting. We will wellcome you soon!