
Seminar | Matinée de l’Intégrité du Génome
Seminar « Functional Genomics of Microsatellite Unstable Tumors and Therapeutic Target Discovery » by Gabriele Picco (Sanger Institute) 11:00 05/12/2025 at Roger Monier.

Seminar « Functional Genomics of Microsatellite Unstable Tumors and Therapeutic Target Discovery » by Gabriele Picco (Sanger Institute) 11:00 05/12/2025 at Roger Monier.

Clara Basto, PhD student of the team of Gerard Mazón/Eric Le Cam under the supervision of Pauline Dupaigne has been awarded the « Prix coup de coeur du Jury » for her talk during the 29th « Journées Jeunes Chercheurs de la Fondation ARC ».

Quantitative molecular cartography of emergency
myelopoiesis reveals conserved modules of hematopoietic
activation
17 Octobre 2025 à 11h30 – Salle Roger Monier (Gustave Roussy)

Masato Kanemaki from the University of Tokyo. (NEW TIME!)
Friday, 17 October at 10:30 at Salle Roger Monier

Christophe Massard
DITEP – Drug Drug development department
“Phase I in 2025”
&
Sergey Nikolaev
New UMR – Cancer Data Center
“Projects of the Cancer Data Center”
Internal Seminar
Tuesday October 14 at 1 PM at the Roger Monier room, PR2.

December 15th 2025: Clara Basto
Molecular study on the roles of RAD51 and its partner proteins in the management of arrested replication forks
(Mazon/Dupaigne Team)
______
December 17th 2025: Basile Guignier
Role of REV3L, the catalytic subunit of DNA polymerase Zeta, in the stability of difficult-to-replicate sequences in mammals
(Kannouche Team)

« Intra-tumoral heterogeneity in small-cell lung cancer development and response to therapy »
Julian Sage (Stanford University, US)
13/10/2025 at 16h
Salle Pierre Denoix (15th Floor Gustave Roussy main builiding)

Prochaine réunion d’unité
13/10/2025
Salle Roger Monier 13h30
Speaker: Nataliya PETRYK
“ Revealing the mechanisms linking genome replication and epigenome maintenance «

The S. Gad group of Ishchenko team leads this work on a novel genetic condition linked to Hereditary renal cell carcinomas (RCC). The team identified a frameshift mutation in NBR1, a gene involved in autophagy. Their findings suggest NBR1 as a potential new RCC predisposition gene, pending further validation.

OK-seq is a technique that sequences strand-specific Okazaki fragments to map replication initiation and termination in mammalian genomes. It quantifies fork directionality, revealing replication dynamics at high resolution. N. Petryk team contributes to this work to provide detailed protocols for OK-seq in human cells and yeast, alongside bioinformatics pipelines.