All Publications & News
Gustave Roussy Cancer Research Lectures | Reuben Harris
"DNA adducting carcinogens exacerbate APOBEC mutagenesis and carcinogenesis" Reuben Harris (UT San Antonio, US) 01/10/2025 at 11h Salle Pierre Denoix
DES BUTS CONTRE LE CANCER
DES BUTS CONTRE LE CANCER - Des stars du football se mobilisent lors d’un match au profit de Gustave Roussy
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
N. Petryk co-authors this review of the mechanisms of DNA methylation in mammals and its biological importance.
Human RAD52 stimulates the RAD51-mediated homology search
In a work led by A. Muhammad, a PhD student under P. Dupaigne supervision in the team, we show that
L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC
L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025
Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis
The AOUFOUCHI team participate in this article : Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of
Retraite de l’unité 16 Octobre 2025
La retraite de l'unité aura lieu le 16 Octobre 2025 à la cité U (Fondation Deutsch de la Meurthe). RDV
Next Unit Lab Meeting
Prochaine réunion d'unité 13/10/2025 Salle Roger Monier 13h30 Speaker: Nataliya PETRYK “ Revealing the mechanisms linking genome replication and epigenome
Monitoring and quantifying replication fork dynamics with high-throughput methods
The N. Petryk lab highlights in this work advances in quantitative technologies that deepen understanding of chromosome replication beyond DNA
DCLRE1B/Apollo germline mutations associated with renal cell carcinoma impair telomere protection
C. Bories, a PhD student under F. Renaud supervision in the Ishchenko team, leads the study identifying germline Apollo gene
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation
B. Rondinelli co-authors this article of the D'Andrea lab describing the roles of EZH2 at stalled replication forks.
Histone Variants: Guardians of Genome Integrity
B. Rondinelli co-authors this review covering the diveristy of Histone varints and their importance for Genome Integrity.
Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors
Beatrice Rondinelli co-authors a study revealing that pediatric high-grade gliomas (pHGG) with H3.3 mutations exhibit aberrant DNA repair promoting genome
Gustave Roussy Cancer Research Lectures | Julien Sage
"Intra-tumoral heterogeneity in small-cell lung cancer development and response to therapy" Julian Sage (Stanford University, US) 13/10/2025 at 16h Salle