All Publications & News

A look back at the event « DES BUTS CONTRE LE CANCER »

€34,000 raised for cancer research

Next Unit Lab Meeting

Prochaine réunion d'unité 13/10/2025 Salle Roger Monier 13h30 Speaker: Nataliya PETRYK “ Revealing the mechanisms linking genome replication and epigenome

Clara Basto, prix Peters at the « Journées JJCC de la Fonation ARC »

Clara Basto, PhD student of the team of Gerard Mazón/Eric Le Cam under the supervision of Pauline Dupaigne has been

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

G. Matos Rodrigues co-authors this work led by the Schatz lab describing the roles of ELOF1 during somatic hypermutation and

Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients

This article is a collaboration of the Kannouche team with the Gustave Roussy's team of S. Nikolaev. Xeroderma pigmentosum (XP)

Re-investigating PLK1 inhibitors as antimitotic agents

Polo-like kinase 1 (PLK1) plays key roles during mitosis, prompting the development of PLK1 inhibitors for anticancer therapy. We recently

Histone Variants: Guardians of Genome Integrity

B. Rondinelli co-authors this review covering the diveristy of Histone varints and their importance for Genome Integrity.

Emmanuelle Pessagué | SEMINAIRE SIRIC EPICURE

Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation 17 Octobre 2025 à 11h30 - Salle Roger

Abasic site-peptide cross-links are blocking lesions repaired by AP endonucleases

A. Ishchenko participates in this study of the fate of the DNA-protein crosslinks generated by the activity of AP endonucleases

Retraite de l’unité 16 Octobre 2025

La retraite de l'unité aura lieu le 16 Octobre 2025 à la cité U (Fondation Deutsch de la Meurthe). RDV

Senataxin and DNA-PKcs redundantly promote non-homologous end joining repair of DNA double strand breaks during V(D)J recombination

G. Matos Rodrigues co-authors this work of the Sleckman lab on the roles of Senataxin and DNA-PKcs during DSB by

Effect of Mismatch repair deficiency on metastasis occurrence in a syngeneic mouse model

This work, led by P. Laplante in Kannouche's team, shows how mismatch repair deficiency causes high mutation rates and microsatellite

Structure and repair of replication-coupled DNA breaks

In this work, authored by G. Matos-Rodrigues. CRISPR-Cas9 nickases, were used to study how replication forks respond to single-strand DNA

L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC

L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025