All Publications & News

Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing

OK-seq is a technique that sequences strand-specific Okazaki fragments to map replication initiation and termination in mammalian genomes. It quantifies

Abasic site-peptide cross-links are blocking lesions repaired by AP endonucleases

A. Ishchenko participates in this study of the fate of the DNA-protein crosslinks generated by the activity of AP endonucleases

16th 3R meeting

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals

N. Petryk co-authors this review of the mechanisms of DNA methylation in mammals and its biological importance.

Unit Seminar: Masato Kanemaki

Masato Kanemaki from the University of Tokyo. (NEW TIME!) Friday, 17 October at 10:30 at Salle Roger Monier

L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC

L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025

Patritumab deruxtecan in HR+HER2- advanced breast cancer: a phase 2 trial

The Kannouche team participate in this article presenting the results of the phase 2 ICARUS-BREAST01 study. The study showed a

Next Thesis Defences

December 15th 2025: Clara Basto Molecular study on the roles of RAD51 and its partner proteins in the management of

ANR AAPG 2026 closing on 14 October 2026

AAPG 2026 of the ANR (1st phase) closing on 14th October

Slx5-Slx8 ubiquitin ligase targets active pools of the Yen1 nuclease to limit crossover formation

Lead by the postdocs of Mazon's team, I. Talhaoui and M. Bernal, the article describes the regulation of Yen1 resolvase

Monitoring and quantifying replication fork dynamics with high-throughput methods

The N. Petryk lab highlights in this work advances in quantitative technologies that deepen understanding of chromosome replication beyond DNA

Seminar | Matinée de l’Intégrité du Génome

Seminar "Functional Genomics of Microsatellite Unstable Tumors and Therapeutic Target Discovery" by Gabriele Picco (Sanger Institute) 11:00 05/12/2025 at Roger

Emmanuelle Pessagué | SEMINAIRE SIRIC EPICURE

Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation 17 Octobre 2025 à 11h30 - Salle Roger

A look back at the event « DES BUTS CONTRE LE CANCER »

€34,000 raised for cancer research