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Emmanuelle Pessagué | SEMINAIRE SIRIC EPICURE
Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation 17 Octobre 2025 à 11h30 - Salle Roger
TASP1-mediated cleavage of REV3L enhances the activity of DNA polymerase ζ in mammalian cells
The Kannouche team contributed to this study, published in Cancer Cell (2026), reporting the results of the ICARUS-LUNG01 Phase II
Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis
The AOUFOUCHI team participate in this article : Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of
Gustave Roussy Cancer Research Lectures | Reuben Harris
"DNA adducting carcinogens exacerbate APOBEC mutagenesis and carcinogenesis" Reuben Harris (UT San Antonio, US) 01/10/2025 at 11h Salle Pierre Denoix
Effect of Mismatch repair deficiency on metastasis occurrence in a syngeneic mouse model
This work, led by P. Laplante in Kannouche's team, shows how mismatch repair deficiency causes high mutation rates and microsatellite
Patritumab deruxtecan in HR+HER2- advanced breast cancer: a phase 2 trial
The Kannouche team participate in this article presenting the results of the phase 2 ICARUS-BREAST01 study. The study showed a
Christophe Massard and Sergey Nikolaev | Internal Seminars at Gustave Roussy
Christophe Massard DITEP – Drug Drug development department “Phase I in 2025” & Sergey Nikolaev New UMR – Cancer Data
DCLRE1B/Apollo germline mutations associated with renal cell carcinoma impair telomere protection
C. Bories, a PhD student under F. Renaud supervision in the Ishchenko team, leads the study identifying germline Apollo gene
16th 3R meeting
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation
B. Rondinelli co-authors this article of the D'Andrea lab describing the roles of EZH2 at stalled replication forks.
Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing
OK-seq is a technique that sequences strand-specific Okazaki fragments to map replication initiation and termination in mammalian genomes. It quantifies
L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC
L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025
Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors
Beatrice Rondinelli co-authors a study revealing that pediatric high-grade gliomas (pHGG) with H3.3 mutations exhibit aberrant DNA repair promoting genome