All Publications & News
Histone Variants: Guardians of Genome Integrity
B. Rondinelli co-authors this review covering the diveristy of Histone varints and their importance for Genome Integrity.
Access to the Electron Microscopy Platform site and forms
Accéder à la page de la plateforme et aux formulaires de contact
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation
B. Rondinelli co-authors this article of the D'Andrea lab describing the roles of EZH2 at stalled replication forks.
Next Unit Lab Meeting
Prochaine réunion d'unité 13/10/2025 Salle Roger Monier 13h30 Speaker: Nataliya PETRYK “ Revealing the mechanisms linking genome replication and epigenome
7th German-french DNA repair Meeting
The 7th German-French DNA repair meeting will be held this November 5th-7th in Paris. The unit is this time involved
Contribution of p53-dependent and -independent mechanisms to upregulation of p21 in Fanconi anemia
F. Rosselli's team shows in this article how abnormal p21 expression in Fanconi anemia (FA) contributes to bone marrow failure
L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC
L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025
Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors
Beatrice Rondinelli co-authors a study revealing that pediatric high-grade gliomas (pHGG) with H3.3 mutations exhibit aberrant DNA repair promoting genome
SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells
In this article, the Mazon's team PhD student H. Dorison goes deeper in the understanding of the SUMO-mediated regulation of
Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis
The AOUFOUCHI team participate in this article : Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of
Monitoring Chk1 kinase activity dynamics in live single cell imaging assays
The ATR/Chk1 pathway regulates cell cycle progression, especially during DNA damage by inducing arrest for repair. Beyond damage response, Chk1
DES BUTS CONTRE LE CANCER
DES BUTS CONTRE LE CANCER - Des stars du football se mobilisent lors d’un match au profit de Gustave Roussy
Changes in the architecture and abundance of replication intermediates at UV-stalled replication forks in human cells
This is a collaborative effort of the Kannouche and Mazon/LeCam teams of the unit. DNA lesions during S phase challenge
16th 3R meeting
