All Publications & News

16th 3R meeting

Séminaire | Auditions Chaires Fondation Gustave Roussy

GR wellcomes Lisa Mangiante and Elsa Bernard to give two talks for the selection of candidates to the "Chair Fondation

Monitoring Chk1 kinase activity dynamics in live single cell imaging assays

The ATR/Chk1 pathway regulates cell cycle progression, especially during DNA damage by inducing arrest for repair. Beyond damage response, Chk1

Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors

Beatrice Rondinelli co-authors a study revealing that pediatric high-grade gliomas (pHGG) with H3.3 mutations exhibit aberrant DNA repair promoting genome

Gustave Roussy Cancer Research Lectures | Julien Sage

"Intra-tumoral heterogeneity in small-cell lung cancer development and response to therapy" Julian Sage (Stanford University, US) 13/10/2025 at 16h Salle

Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors

The S. Gad group of Ishchenko team leads this work on a novel genetic condition linked to Hereditary renal cell

Clara Basto, prix Peters at the « Journées JJCC de la Fonation ARC »

Clara Basto, PhD student of the team of Gerard Mazón/Eric Le Cam under the supervision of Pauline Dupaigne has been

A look back at the event « DES BUTS CONTRE LE CANCER »

€34,000 raised for cancer research

Unit Seminar: Masato Kanemaki

Masato Kanemaki from the University of Tokyo. (NEW TIME!) Friday, 17 October at 10:30 at Salle Roger Monier

Restriction of Ku translocation protects telomere ends

In a collaborative effort, the Mazon/Le Cam team used Cryo-EM to reveal how Rap1 inhibits Ku’s NHEJ activity at telomeres.

Histone Variants: Guardians of Genome Integrity

B. Rondinelli co-authors this review covering the diveristy of Histone varints and their importance for Genome Integrity.

Christophe Massard and Sergey Nikolaev | Internal Seminars at Gustave Roussy

Christophe Massard DITEP – Drug Drug development department “Phase I in 2025” & Sergey Nikolaev New UMR – Cancer Data

Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis

The AOUFOUCHI team participate in this article : Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

G. Matos Rodrigues co-authors this work led by the Schatz lab describing the roles of ELOF1 during somatic hypermutation and