All Publications & News

DES BUTS CONTRE LE CANCER

DES BUTS CONTRE LE CANCER - Des stars du football se mobilisent lors d’un match au profit de Gustave Roussy

Contribution of p53-dependent and -independent mechanisms to upregulation of p21 in Fanconi anemia

F. Rosselli's team shows in this article how abnormal p21 expression in Fanconi anemia (FA) contributes to bone marrow failure

Slx5-Slx8 ubiquitin ligase targets active pools of the Yen1 nuclease to limit crossover formation

Lead by the postdocs of Mazon's team, I. Talhaoui and M. Bernal, the article describes the regulation of Yen1 resolvase

Structure and repair of replication-coupled DNA breaks

In this work, authored by G. Matos-Rodrigues. CRISPR-Cas9 nickases, were used to study how replication forks respond to single-strand DNA

Human RAD52 stimulates the RAD51-mediated homology search

In a work led by A. Muhammad, a PhD student under P. Dupaigne supervision in the team, we show that

Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors

The S. Gad group of Ishchenko team leads this work on a novel genetic condition linked to Hereditary renal cell

7th German-french DNA repair Meeting

The 7th German-French DNA repair meeting will be held this November 5th-7th in Paris. The unit is this time involved

Séminaire | Auditions Chaires Fondation Gustave Roussy

GR wellcomes Lisa Mangiante and Elsa Bernard to give two talks for the selection of candidates to the "Chair Fondation

Histone Variants: Guardians of Genome Integrity

B. Rondinelli co-authors this review covering the diveristy of Histone varints and their importance for Genome Integrity.

Abasic site-peptide cross-links are blocking lesions repaired by AP endonucleases

A. Ishchenko participates in this study of the fate of the DNA-protein crosslinks generated by the activity of AP endonucleases

Monitoring and quantifying replication fork dynamics with high-throughput methods

The N. Petryk lab highlights in this work advances in quantitative technologies that deepen understanding of chromosome replication beyond DNA

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

G. Matos Rodrigues co-authors this work led by the Schatz lab describing the roles of ELOF1 during somatic hypermutation and

16th 3R meeting

Retraite de l’unité 16 Octobre 2025

La retraite de l'unité aura lieu le 16 Octobre 2025 à la cité U (Fondation Deutsch de la Meurthe). RDV