All Publications & News

Human RAD52 stimulates the RAD51-mediated homology search

In a work led by A. Muhammad, a PhD student under P. Dupaigne supervision in the team, we show that

Gustave Roussy Cancer Research Lectures | Reuben Harris

"DNA adducting carcinogens exacerbate APOBEC mutagenesis and carcinogenesis" Reuben Harris (UT San Antonio, US) 01/10/2025 at 11h Salle Pierre Denoix

Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing

OK-seq is a technique that sequences strand-specific Okazaki fragments to map replication initiation and termination in mammalian genomes. It quantifies

DES BUTS CONTRE LE CANCER

DES BUTS CONTRE LE CANCER - Des stars du football se mobilisent lors d’un match au profit de Gustave Roussy

Access to the Electron Microscopy Platform site and forms

Accéder à la page de la plateforme et aux formulaires de contact

A look back at the event « DES BUTS CONTRE LE CANCER »

€34,000 raised for cancer research

Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors

The S. Gad group of Ishchenko team leads this work on a novel genetic condition linked to Hereditary renal cell

Re-investigating PLK1 inhibitors as antimitotic agents

Polo-like kinase 1 (PLK1) plays key roles during mitosis, prompting the development of PLK1 inhibitors for anticancer therapy. We recently

Next Thesis Defences

December 15th 2025: Clara Basto Molecular study on the roles of RAD51 and its partner proteins in the management of

16th 3R meeting

Retraite de l’unité 16 Octobre 2025

La retraite de l'unité aura lieu le 16 Octobre 2025 à la cité U (Fondation Deutsch de la Meurthe). RDV

EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation

B. Rondinelli co-authors this article of the D'Andrea lab describing the roles of EZH2 at stalled replication forks.

L’équipe des « Gardiens du Génome » finisse en 5ème place au tournoi KOC

L'équipe des "Gardiens du Génome" cartonne au KOC du 13/09/2025

7th German-french DNA repair Meeting

The 7th German-French DNA repair meeting will be held this November 5th-7th in Paris. The unit is this time involved