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A look back at the event « DES BUTS CONTRE LE CANCER »
€34,000 raised for cancer research
Gustave Roussy Cancer Research Lectures | Reuben Harris
"DNA adducting carcinogens exacerbate APOBEC mutagenesis and carcinogenesis" Reuben Harris (UT San Antonio, US) 01/10/2025 at 11h Salle Pierre Denoix
DES BUTS CONTRE LE CANCER
DES BUTS CONTRE LE CANCER - Des stars du football se mobilisent lors d’un match au profit de Gustave Roussy
Next Thesis Defences
December 15th 2025: Clara Basto Molecular study on the roles of RAD51 and its partner proteins in the management of
Gustave Roussy Cancer Research Lectures | Julien Sage
"Intra-tumoral heterogeneity in small-cell lung cancer development and response to therapy" Julian Sage (Stanford University, US) 13/10/2025 at 16h Salle
Changes in the architecture and abundance of replication intermediates at UV-stalled replication forks in human cells
This is a collaborative effort of the Kannouche and Mazon/LeCam teams of the unit. DNA lesions during S phase challenge
Next Unit Lab Meeting
Prochaine réunion d'unité 13/10/2025 Salle Roger Monier 13h30 Speaker: Nataliya PETRYK “ Revealing the mechanisms linking genome replication and epigenome
Christophe Massard and Sergey Nikolaev | Internal Seminars at Gustave Roussy
Christophe Massard DITEP – Drug Drug development department “Phase I in 2025” & Sergey Nikolaev New UMR – Cancer Data
Structure and repair of replication-coupled DNA breaks
In this work, authored by G. Matos-Rodrigues. CRISPR-Cas9 nickases, were used to study how replication forks respond to single-strand DNA
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation
B. Rondinelli co-authors this article of the D'Andrea lab describing the roles of EZH2 at stalled replication forks.
Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing
OK-seq is a technique that sequences strand-specific Okazaki fragments to map replication initiation and termination in mammalian genomes. It quantifies
Patritumab deruxtecan in HR+HER2- advanced breast cancer: a phase 2 trial
The Kannouche team participate in this article presenting the results of the phase 2 ICARUS-BREAST01 study. The study showed a
DCLRE1B/Apollo germline mutations associated with renal cell carcinoma impair telomere protection
C. Bories, a PhD student under F. Renaud supervision in the Ishchenko team, leads the study identifying germline Apollo gene
Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors
The S. Gad group of Ishchenko team leads this work on a novel genetic condition linked to Hereditary renal cell